Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (UniProt)
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human NBS1 / NBN was used as the immunogen for the NBS1 antibody.
Isotype
IgG
Predicted Reactivity
Human, Rat
Reactivity
Human, Rat
Recombinant
No
Subcellular Location
Nuclear
Antigen
NBS1
Uniprot
O60934
Clone No
COF-14
Format
Purified
Purification
Affinity purified
Storage
Store the NBS1 antibody at -20°C.
Applications
IHC-P, WB
Dilution
Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:50-1:200