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Home / Primary Antibodies / Monoclonal Antibodies

Mucin-1 Antibody / MUC1 (beta subunit)

SKU : BHA17110117

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NSJ Bioreagents

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Mfr.No.	RQ5459
Clonality	Monoclonal
Description	The MUC1 gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to the C-terminal region (beta subunit) of human MUC1 / Mucin-1 was used as the immunogen for the Mucin-1 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	MUC1
Uniprot	P15941
Clone No	FHA-13

Format	Purified
Purification	Affinity purified
Storage	Store the Mucin-1 antibody at -20°C.

Applications	IHC-P, WB
Dilution	Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:50-1:200

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110117	RQ5459	100ul	$439		Add to Cart

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