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Home / Primary Antibodies / Monoclonal Antibodies

MMP2 Antibody

SKU : BHA17102341

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Mfr.No.	F53512, F53512-0.1ML
Clonality	Monoclonal
Description	Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-\|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.<p> PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. (UniProt)
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	This MMP2 antibody was produced from mouse immunized with MMP2 recombinant protein.
Isotype	IgG2b,k
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	MMP2
Uniprot	P08253
Clone No	6E3F8

Format	Ascites
Purification	Ascites
Storage	Aliquot the MMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB, ELISA
Dilution	Western blot: 1:200-1:1000,IHC (Paraffin): 1:50-1:100

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102341	F53512, F53512-0.1ML	0.1ml	$429		Add to Cart

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