This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. (RefSeq)
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human M6PR / IGF2R was used as the immunogen for the M6PR antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Subcellular Location
Cytoplasmic
Antigen
IGF2R
Uniprot
P11717
Clone No
DIC-9
Format
Purified
Purification
Affinity purified
Storage
Store the M6PR antibody at -20°C.
Applications
IHC-P, WB
Dilution
Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:50-1:200