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Home / Primary Antibodies / Monoclonal Antibodies

KEAP1 antibody

SKU : BHA10804509

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Mfr.No.	FNab04517
Alternative Names	INRF2 ; KIAA0132 ; KLHL19
Background	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Host	Mouse
Immunogen	kelch-like ECH-associated protein 1
Isotype	IgG2a
Molecular Weight	55-70 kDa
Reactivity	Human, Rat, Mouse
Regulatory	RUO
Synonyms	INRF2, KIAA0132, KLHL19

Uniprot	Q14145
Gene Id	9817
Clone No	9E2
Research Area	Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804509	FNab04517	100ug	$260		Add to Cart

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