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Home / Primary Antibodies / Monoclonal Antibodies

KEAP1 antibody

SKU : BHA10804509

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Mfr.No.	FNab04517
Alternative Names	INRF2 ; KIAA0132 ; KLHL19
Background	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Host	Mouse
Immunogen	kelch-like ECH-associated protein 1
Isotype	IgG2a
Molecular Weight	55-70 kDa
Reactivity	Human, Rat, Mouse
Regulatory	RUO
Synonyms	INRF2, KIAA0132, KLHL19

Antigen	Keap1
Uniprot	Q14145
Gene Id	9817
Clone No	9E2
Research Area	Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804509	FNab04517	100ug	$260		Add to Cart

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