HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1. It is mapped to 1p12. The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids.
Host
Rabbit
Immunogen Region
Recombinant human protein (amino acids Q17-Q373) was used as the immunogen for the HSD3B1/2 antibody.
Isotype
Rabbit IgG
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
HSD3B1/2
Uniprot
P14060
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the HSD3B1/2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Applications
IF, WB
Dilution
Western blot: 1-2ug/ml,Immunofluorescence (FFPE): 5ug/ml