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Home / Primary Antibodies / Monoclonal Antibodies

HLA-G antibody

SKU : BHA10809941

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Mfr.No.	FNab09952
Background	Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted patte of expression that includes placental extravillous trophoblasts at the mateal-fetal interface, where it abolishes mateal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Clonality	monoclonal
Host	Mouse
Immunogen	MHC class I antigen G
Immunogen Region	MHC class I antigen G
Isotype	IgG1
Molecular Weight	38 kDa
Reactivity	Human
Recommended Dilution	WB: 1:2000-1:10000; IHC: 1:50-1:200
Synonyms	HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G

Uniprot	P17693
Gene Id	3135
Clone No	3C12
Research Area	Immunology

Form	liquid
Purification	protein A+G purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:2000-1:10000; IHC: 1:50-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09952.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809941	FNab09952	100ug	$280		Add to Cart

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