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Home / Primary Antibodies / Monoclonal Antibodies

Galectin-3

SKU : BHA15100469

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Mfr.No.	AMB39-5M
Clonality	Monoclonal
Description	Galectin 3 also designated as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, belongs to galectin family which are soluble b-galactoside-binding animal lectins. They modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galcetin-3 is a chimera galectin that has a tendency to dimerize. It promotes cell growth and proliferation for many cell types. Galectin-3 acts intracellularly to prevent apoptosis. It exhibits pro- or anti-adhesive properties on different type of cells. Galectin-3 chemoattracts monocytes and macrophages. It activates and degranulates basophils and mast cells. Galectin-3 is expressed in tumor cells, osteoclasts, epithelial cells, fibroblasts, colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. It binds various matrix glycoproteins including laminin, fibronectin, LAMPS, 90K/Mac-2BP, MP20, and CEA. Elevated circulating levels of Galectin-3 have been show to correlate with the malignant potential of several types of cancer, suggesting that Galectin-3 is also involved in tumor growth and metastasis.
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	B2C10
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMB39-5M	AMB39-5M	6 mL	$355		Add to Cart
AMB39-10M	AMB39-10M	100 tests - i6000	$664		Add to Cart
AXB39-50D	AXB39-50D	50 tests - Xmatrx	$373		Add to Cart
AXB39-YCD	AXB39-YCD	160 tests - Xmatrx	$909		Add to Cart
MUB39-UC	MUB39-UC	1ml Conc	$728		Add to Cart
MUB39-5UC	MUB39-5UC	0.5ml Conc	$509		Add to Cart

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