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Home / Primary Antibodies / Monoclonal Antibodies

FITC Anti-Mouse CD105 Antibody[MJ7/18]

SKU : BHA10326832

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1233C
Antigen	CD105, CD105
Background	CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-beta1, TGF-beta3 and modulates TGF-beta signaling by interacting with TGF-beta receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases., CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-?1, TGF-?3 and modulates TGF-? signaling by interacting with TGF-? receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Clonality	Monoclonal
Conjugate	FITC
Host	Rat
Immunogen	0, 0
Isotype	Rat IgG2a, kappa
Reactivity	Mouse

Clone No	MJ7/18, MJ7/18

Buffer	PBS with 0.05% Proclin300, 1% BSA, PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze., Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM, FCM

Product Manual	Data Sheet, <a href="https://file.elabscience.com/viewpdf-376689-Elabscience-E-AB-F1233C.pdf" target="_blank">Data Sheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10326832	E-AB-F1233C	20Tests	$55		Add to Cart
BHA10326832	E-AB-F1233C	50Tests	$85		Add to Cart
BHA10326832	E-AB-F1233C	100Tests	$145		Add to Cart
BHA10326832	E-AB-F1233C	200Tests	$220		Add to Cart

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