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Home / Primary Antibodies / Monoclonal Antibodies

Filaggrin

SKU : BHA15100467

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Mfr.No.	AMB37-5M
Clonality	Monoclonal
Description	Filaggrin protein is an intermediate filament-associated protein that aggregates keratin intermediate filaments in epidermis. It is initially synthesized as a polyprotein precursor molecule, profilaggrin (a large, insoluble, highly phosphorylated precursor protein containing several tandem copies of a 324 amino acid). Profilaggrin is proteolytically processed into active filaggrin molecules and these molecules promote aggregation by forming disulfide-bond of keratin intermediate filaments during terminal differentiation of the epidermis. Filaggrin expression is seen only in well differentiated keratinized epithelial cells. Mutations in this gene are associated with ichthyosis vulgaris with viral, premalignant and malignant conditions.
Host	Mouse
Isotype	IgG1, Kappa
Reactivity	Human
Species	Mouse

Clone No	FLG/1562
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMB37-5M	AMB37-5M	6 mL	$276		Add to Cart
AMB37-10M	AMB37-10M	100 tests - i6000	$517		Add to Cart
AXB37-50D	AXB37-50D	50 tests - Xmatrx	$290		Add to Cart
AXB37-YCD	AXB37-YCD	160 tests - Xmatrx	$725		Add to Cart
MUB37-UC	MUB37-UC	1ml Conc	$566		Add to Cart
MUB37-5UC	MUB37-5UC	0.5ml Conc	$396		Add to Cart

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