Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. The DES gene encodes a cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that Desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Mutations are responsible for idiopathic dilated cardiomyopathy.
Formulation
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Host
Mouse
Immunogen Region
Desmin from pig stomach was used as the immunogen for this Desmin antibody.
Isotype
IgG1
Predicted Reactivity
Human, mouse, rat, rabbit
Reactivity
Human, Mouse, Rat, Rabbit
Recombinant
No
Antigen
Desmin
Gene Id
1674
Clone No
DE-U-10
Format
Ascites
Purification
Unpurified ascites
Storage
After reconstitution, the Desmin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.