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Home / Primary Antibodies / Monoclonal Antibodies

CUBN Antibody / Cubilin

SKU : BHA17109534

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NSJ Bioreagents

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Mfr.No.	RQ4757
Clonality	Monoclonal
Description	Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface. (UniProt)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human Cubilin / CUBN was used as the immunogen for the CUBN antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic, membrane

Antigen	Cubilin
Uniprot	O60494
Clone No	GA-3

Format	Purified
Purification	Affinity purified
Storage	Store the CUBN antibody at -20°C.

Applications	IHC-P, WB
Dilution	Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109534	RQ4757	100ul	$439		Add to Cart

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