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Home / Primary Antibodies / Monoclonal Antibodies

COPS5 Antibody / JAB1

SKU : BHA17122798

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NSJ Bioreagents

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Mfr.No.	RQ6537
Clonality	Monoclonal (mouse origin)
Description	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Mouse
Immunogen Region	An E. coli-derived human protein (amino acids M8-S334) was used as the immunogen for the COPS5 antibody.
Isotype	Mouse IgG2b
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the COPS5 antibody should be determined by the researcher.

Uniprot	Q92905

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the COPS5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, IF, FACS
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122798	RQ6537	100ug	$439		Add to Cart

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