CEA is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
Host
Mouse
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
CEA is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
Species
Homo Sapiens (Human)
Specificity
The CEA Mouse Monoclonal Antibody detects endogenous CEA proteins.
Antigen
CEACAM5 Monoclonal
Buffer
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Description
The CEA Mouse Monoclonal Antibody detects endogenous CEA proteins.
Form
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antigen Affinity Purified
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Applications
ELISA, IHC
Description
ELISA ; IHC, IHC ; ELISA
Dilution
IHC
1:50-1:200
Tested Application
ELISA,IHC;Recommended dilution:IHC:1:50-1:200
Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Reviews of CEACAM5 Monoclonal Antibody (CSB-MA086677)