CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. The Cyclin dependent kinase7 gene is mapped to chromosome 2p15-cen. Cdk7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of Cdk1 activation are mutually dependent.
Formulation
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Host
Mouse
Immunogen Region
Recombinant human protein was used as the immunogen for this Cdk7 antibody.
Isotype
IgG2b
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
Cdk7
Gene Id
1022
Clone No
IMD-26
Format
Ascites
Purification
Ascites
Storage
After reconstitution, the Cdk7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
IHC-F, WB, ICC
Dilution
Western blot: 0.25ug/ml,Immunohistochemistry (Frozen): 0.5ug/ml-formalin/acetone fixed tissues,Immunocytochemistry: Suitable