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Home / Primary Antibodies / Monoclonal Antibodies

CD44 antibody

SKU : BHA10801478

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Mfr.No.	FNab01483
Alternative Names	LHR ; MDU2 ; MDU3 ; MIC4
Background	Receptor for hyaluronic acid(HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases(MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T(iTreg) cell stability and suppressive function(By similarity).
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	monoclonal
Description	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Host	Mouse
Immunogen	CD44 molecule(Indian blood group)
Isotype	IgG2a
Molecular Weight	80-95 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Cell membrane
Synonyms	LHR, MDU2, MDU3, MIC4

Uniprot	P16070
Gene Id	960
Clone No	7D6
Research Area	Stem Cells, Immunology, Cardiovascular, Cancer
Weight	82kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF, FC

Description

ELISA ; WB ; IHC ; IF ; FC

Dilution

WB	1:500-1:5000
IHC	1:50-1:200
IF	1:10-1:100

Tested Application

WB: 1?500-1?5000; IHC: 1?50-1?200; IF: 1?10-1?100

Manual	FNab01483.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801478	FNab01483	100ug	$260		Add to Cart

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