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Home / Primary Antibodies / Monoclonal Antibodies

CD3 epsilon antibody

SKU : BHA10801454

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Mfr.No.	FNab01459
Background	CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	CD3e molecule, epsilon (CD3-TCR complex)
Isotype	IgG1
Molecular Weight	23 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Uniprot	P07766
Gene Id	916
Clone No	2E4
Research Area	Cancer, Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, FC
Description	ELISA ; WB ; IHC ; FC
Tested Application	WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500

Manual	FNab01459.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801454	FNab01459	100ug	$260		Add to Cart

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