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Home / Primary Antibodies / Monoclonal Antibodies

CCND1 Antibody

SKU : BHA17127905

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NSJ Bioreagents

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Mfr.No.	V9073IHC, V9073IHC-7ML
Clonality	Monoclonal (mouse origin)
Description	Cyclin D1 (CCND1), one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of Cyclin D1. This antibody is useful in identifying mantle cell lymphomas (CCND1+) from CLL/SLL and follicular lymphomas (CCND1-). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express CCND1.
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Mouse
Immunogen Region	Recombinant full length human protein was used as the immunogen for this CCND1 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human, Mouse
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P24385

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CCND1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/ccnd1-antibody-spm587-v9073" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127905	V9073IHC, V9073IHC-7ML	7ml	$539		Add to Cart

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