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Home / Primary Antibodies / Monoclonal Antibodies

CASR Antibody / Calcium Sensing Receptor

SKU : BHA17109297

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NSJ Bioreagents

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Mfr.No.	RQ4484
Clonality	Monoclonal
Description	The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Mouse
Immunogen Region	Human CASR recombinant protein (amino acids Q926-S1078) was used as the immunogen for the CASR antibody.
Isotype	IgG2b
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cell membrane

Antigen	Calcium Sensing Receptor
Uniprot	P41180
Clone No	11E9-

Buffer	Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Format	Purified
Purification	Protein G affinity
Storage	After reconstitution, the CASR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	FACS, WB
Dilution	Western blot: 0.5-1ug/ml (human),Flow Cytometry: 1-3ug/1xmillion cells (mouse)

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109297	RQ4484	100ug	$439		Add to Cart

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