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Home / Primary Antibodies / Monoclonal Antibodies

BMI1 antibody

SKU : BHA10800909

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Mfr.No.	FNab00914
Alternative Names	PCGF4 ; RNF51
Background	Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Host	Mouse
Immunogen	BMI1 polycomb ring finger oncogene
Isotype	IgG1
Molecular Weight	37 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51

Uniprot	P35226
Gene Id	648
Clone No	8D5
Research Area	Epigenetics, Developmental biology, Cell Division and Proliferation, Metabolism, Cancer, Stem Cells

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800909	FNab00914	100ug	$260		Add to Cart

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