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Home / Primary Antibodies / Monoclonal Antibodies

Beclin 1 antibody

SKU : BHA10810662

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Mfr.No.	FNab10873
Background	Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Clonality	monoclonal
Host	Mouse
Immunogen	beclin 1, autophagy related
Immunogen Region	beclin 1, autophagy related
Isotype	IgG1
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:5000; IHC: 1:50 - 1:200
Synonyms	ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30

Uniprot	Q14457
Gene Id	8678
Clone No	1G5
Research Area	Cancer, Immunology, Metabolism

Form	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:5000; IHC: 1:50 - 1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10875.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810662	FNab10873	100ug	$300		Add to Cart

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