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Home / Primary Antibodies / Monoclonal Antibodies

Anti-SOX2

SKU : BHA15100283

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BioGenex Laboratories

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Mfr.No.	AR788-5R
Clonality	Polyclonal
Description	SOX2 or SRY related HMG BOX gene 2 is a transcription factor belongs to the SRY-related HMG-box (SOX) and it is involved in the regulation of embryonic development, determination of cell fate. SOX2 factor is critical for stem cell potency in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for Oct3/4 regulation, expression . An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression. Structurally SOX proteins posses a single HMG box and bind to linearized DNA in a sequence-specific manner, results in the bending of DNA through large angles. Bending results in DNA helix to open, it affects binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution
Host	Rabbit
Isotype	NA
Reactivity	Human
Species	Rabbit

Clone No	Polyclonal
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AR788-5R	AR788-5R	6 mL	$234		Add to Cart
AR788-10R	AR788-10R	100 tests - i6000	$395		Add to Cart
AW788-50D	AW788-50D	50 tests - Xmatrx	$242		Add to Cart
AW788-YCD	AW788-YCD	160 tests - Xmatrx	$633		Add to Cart
PU788-UP	PU788-UP	1ml Conc	$331		Add to Cart
PU788-5UP	PU788-5UP	0.5ml Conc	$234		Add to Cart

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