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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PAX5 Antibody Picoband® (monoclonal, 6I4)

SKU : BHA21002276

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Mfr.No.	M00669-2, M00669-2-10ug, M00669-2-Biotin, M00669-2-Cy3, M00669-2-Dylight488, M00669-2-Dylight550, M00669-2-Dylight594, M00669-2-FITC, M00669-2-HRP, M00669-2-APC, M00669-2-PE, M00669-2-iFluor647, M00669-2-carrier-free
Alternative Names	paired box 5
Background	Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PAX5 Antibody Picoband® (monoclonal, 6I4) catalog # M00669-2. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Host	Mouse
Immunogen Region	E. coli-derived human PAX5 recombinant protein (Position: R217-A282).
Isotype	Mouse IgG2b
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Paired box protein Pax-5; B-cell-specific transcription factor; BSAP; PAX5
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q02548
Gene Id	5079
Gene Name	PAX5
Clone No	Clone: 6I4
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human

Reference	1. Adams B, Dörfler P, Aguzzi A, Kozmik Z, Urbánek P, Maurer-Fogy I, Busslinger M (Sep 1992). "Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis". Genes & Development. 6 (9): 1589607. <br /><br />2. Pilz AJ, Povey S, Gruss P, Abbott CM (March 1993). "Mapping of the human homologs of the murine paired-box-containing genes". Mammalian Genome. 4 (2): 7882.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002276-1	M00669-2	-	100 ug	$370		Add to Cart
BHA21002276-2	M00669-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002276-3	M00669-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002276-4	M00669-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002276-5	M00669-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002276-6	M00669-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002276-7	M00669-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002276-8	M00669-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002276-9	M00669-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002276-10	M00669-2-APC	APC	100 ug	$670		Add to Cart
BHA21002276-11	M00669-2-PE	PE	100 ug	$670		Add to Cart
BHA21002276-12	M00669-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002276-13	M00669-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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