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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Kappa Light Chain

SKU : BHA15100374

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BioGenex Laboratories

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Mfr.No.	AM980-5M
Clonality	Monoclonal
Description	There are two types of light chain in humans (Kappa (?) Light Chain and Lambda (?) Light Chain. Normally, the total Kappa to Lambda ratio is about 2:1 in serum, with a highly divergent ratio indicative of neoplasm. If one type of light chain level is significantly higher than that of the other type, it indicates a malignant condition, such as B-cell lymphoma. This antibody is designed specific for Kappa Light Chain of Immunoglobulin, as a B cell marker. Detection of gene rearrangements and abnormal expression of Kappa Light Chain in immunoglobulin, are important methods in the diagnosis of B-cell lymphoma, Plasma cell myeloma, and Reactive follicular hyperplasia. The most important role of the antibody would be in distinguishing atypical reactive follicular lymphoid hyperplasia from follicular lymphoma. In general, the neoplastic cells of follicle-like arrangement in extramedullary plasmacytoma and extracellular material are positive for Kappa Light Chain.
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	HP6053+L1C1
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-40

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM980-5M	AM980-5M	6 mL	$200		Add to Cart
AM980-10M	AM980-10M	100 tests - i6000	$336		Add to Cart
AX980-50D	AX980-50D	50 tests - Xmatrx	$204		Add to Cart
AX980-YCD	AX980-YCD	160 tests - Xmatrx	$536		Add to Cart
MU980-UC	MU980-UC	1ml Conc	$302		Add to Cart
MU980-5UC	MU980-5UC	0.5ml Conc	$212		Add to Cart

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