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Home / Primary Antibodies / Conjugated Primary Antibodies

anti-human TCR C beta

SKU : BHA14700001

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Ancell Corporation

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Mfr.No.	101, 101-020, 101-030, 101-040, 101-050, 101-060, 101-820
Alternative Names	TCRCb1, TRBC1, TRBC-1
Background	Human T cell receptor (TCR) is a T cell surface expressed heterodimer of α/β or γ/δ chains. TCR's recognize antigen peptides bound to MHC molecules forming the basis of antigen specific response by T cells. Antibody JOVI-1 recognizes human Cβ1 TCR gene product and reacts with 50-75% of T cells in normal human blood. Antibody JOVI-1 is mitogenic for T cells expressing TCR Cβ1.
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Host	Mouse
Isotype	IgG2a
Reactivity	Human
Specificity	Antibody JOVI-1 recognizes human C beta 1 TCR gene product and reacts with 50-75% of T cells in normal human blood (1). JOVI-1 does not bind to TCR C beta 2 (5).

Purity	Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Purity was >95% Immunoglobulin by SDS-PAGE and contains less than 1% Bovine Immunoglobulin.
Storage	Store at 2 - 5°C. Freeze/Thawing is not recommended.
Storage Buffer	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Applications	FC

Product Manual	Data Sheet

Reference	1. J.L. Viney, et al, (1992) Hybridoma 11: 701-713. PMID: 1284120 2. A. Weiss, (1993) Cell 73: 209-212. 3. M.M. Daris, (1995) Nature 375: 104. 4. S. Valitutti, et al, (1995) Nature 375: 148-151. 5. Paul M Maciocia, Martin A Pule, et al. (2017) Nature Medicine 23: 1416-1423. doi: 10.1038/nm.4444. Epub 2017 Nov 13. PMID: 29131157 6. M Shi, P Horn, et al. (April 11, 2019) Clinical Cytometry https://doi.org/10.1002.cyto.b.21782 7. H Berg, H Olteanu, et al. (April 2020) Clinical Cytometry https://doi.org/10.1002/cyto.b.21881 8. P. Horna, Min Shi, et al. (2021) Am J Clin Pathol 156(1): 139-148. doi: 10.1093/ajcp/aqaa214.doi: 10.1093/ajcp/aqaa214.

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA14700001-1	101-020	Pur WA	100 ug	$300		Add to Cart
BHA14700001-2	101-030	Biotin	100 ug	$450		Add to Cart
BHA14700001-3	101-040	FITC	120 tests	$450		Add to Cart
BHA14700001-4	101-050	PE	120 tests	$550		Add to Cart
BHA14700001-5	101-060	APC	120 tests	$550		Add to Cart
BHA14700001-6	101-820	Pur/PF	100 ug	$300		Add to Cart

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