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Home / Primary Antibodies / Monoclonal Antibodies

anti-human MHC Class I

SKU : BHA14700004

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Ancell Corporation

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Mfr.No.	121, 121-020, 121-030, 121-040, 121-050, 121-820
Alternative Names	HLA-A, HLA-B, HLA-C, Major Histocompatibility complex
Background	Human MHC Class I (HLA-A, B & C) molecules are expressed on nearly all nucleated cells. MHC Class I molecules consist of heterodimers of a highly polymorphic transmembrane ? chain and an invariant ? chain. MHC Class I molecules bind to enDogenously synthesized peptides of about 8-10 amino acids which are presented to CD8+ T cells. Recent evidence now indicates exogenously derived peptides are also presented by MHC Class I molecules. Antibody 3F10 recognizes a monomorphic Class I epitope on the ? chain.
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Host	Mouse
Isotype	IgG2a
Reactivity	Human
Specificity	Antibody 3F10 recognizes a monomorphic Class I epitope on the alpha chain (1). It has been reported to cross react with canine Class I (9).

Purity	Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Purity was >95% Immunoglobulin by SDS-PAGE with less than 1% Bovine Immunoglobulin.
Storage	Store at 2 - 5°C. Freeze/Thawing is not recommended.
Storage Buffer	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Applications	EIA, FC, IHC

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA14700004-1	121-020	Pur WA	100 ug	$200		Add to Cart
BHA14700004-2	121-030	Biotin	100 ug	$235		Add to Cart
BHA14700004-3	121-040	FITC	120 tests	$235		Add to Cart
BHA14700004-4	121-050	PE	120 tests	$300		Add to Cart
BHA14700004-5	121-820	Pur/PF	100 ug	$200		Add to Cart

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