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Home / Primary Antibodies / Monoclonal Antibodies

Anti-HSD3B1 Antibody Picoband® (monoclonal, 3F3C/7F9C8)

SKU : BHA21003826

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Mfr.No.	M02856, M02856-10ug, M02856-Biotin, M02856-Cy3, M02856-Dylight488, M02856-Dylight550, M02856-Dylight594, M02856-FITC, M02856-HRP, M02856-APC, M02856-PE, M02856-iFluor647, M02856-carrier-free
Alternative Names	high mobility group box 3
Background	HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1. It is mapped to 1p12. The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-HSD3B1 Antibody Picoband® (monoclonal, 3F3C/7F9C8) catalog # M02856. Tested in IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Multifunctional protein with various roles in different cellular compartments,May act in a redox sensitive manner.Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enha
Host	Mouse
Immunogen Region	E.coli-derived human HSD3B1 recombinant protein (Position: Q17-Q373).
Isotype	Mouse IgG2b
Molecular Weight	42 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	"chromosomal protein, Nonhistone, HMG4 antibody\|High mobility group (nonhistone chromosomal) protein 4 antibody\|High mobility group box 3 antibody\|High mobility group protein 2a antibody\|High mobility group protein 4 antibody\|High mobility group protein B3 antibody\|High mobility group protein HMG4 antibody\|HMG 4 antibody\|HMG-2a antibody\|HMG-4 antibody\|HMG2A antibody\|HMGB 3 antibody\|HMGB3 antibody\| HMGB3_HUMAN antibody\|MGC90319 antibody\|Non histone chromosomal protein antibody\|Nonhistone chromosomal protein HMG4 antibody"
Tissue Specificity	Expressed predominantly in placenta.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P14060
Gene Id	3283
Gene Name	HSD3B1
Clone No	Clone: 3F3C/7F9C8
Subcellular Location	Nucleus . Chromosome . Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, ICC, IF
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human

Reference	1. Taneja SS (January 2017). "Re: HSD3B1 and Resistance to Androgen-Deprivation Therapy in Prostate Cancer: A Retrospective, Multicohort Study". The Joual of Urology. 197 (1): 150. 2. Hea, Jason (October 2016). "HSD3B1 and resistance to androgen-deprivation therapy in prostate cancer: a retrospective, multicohort study". Lancet Oncology. 17 (10): 14351444. 3. Russell AJ, Gaffney D, Gardiner MT, Nickson DA, Sutcliffe RG (March 1991). "Synonymous polymorphism in the coding sequence of human 3-beta hydroxysteroid-5-ene dehydrogenase (HSD)". Nucleic Acids Research. 19 (5): 1172.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003826-1	M02856	-	100 ug	$370		Add to Cart
BHA21003826-2	M02856-10ug	Sample	10 ug	$99		Add to Cart
BHA21003826-3	M02856-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003826-4	M02856-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003826-5	M02856-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003826-6	M02856-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003826-7	M02856-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003826-8	M02856-FITC	FITC	100 ug	$570		Add to Cart
BHA21003826-9	M02856-HRP	HRP	100 ug	$570		Add to Cart
BHA21003826-10	M02856-APC	APC	100 ug	$670		Add to Cart
BHA21003826-11	M02856-PE	PE	100 ug	$670		Add to Cart
BHA21003826-12	M02856-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003826-13	M02856-carrier-free	carrier-free	100 ug	$370		Add to Cart

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