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Home / Primary Antibodies / Monoclonal Antibodies

Anti-DCK Antibody Picoband® (monoclonal, 3G10)

SKU : BHA21002381

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Mfr.No.	M01655, M01655-10ug, M01655-Biotin, M01655-Cy3, M01655-Dylight488, M01655-Dylight550, M01655-Dylight594, M01655-FITC, M01655-HRP, M01655-APC, M01655-PE, M01655-iFluor647, M01655-carrier-free
Alternative Names	deoxycytidine kinase
Background	Deoxycytidine kinase (dCK) is an enzyme which is encoded by the DCK gene in humans. Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-DCK Antibody Picoband® (monoclonal, 3G10) catalog # M01655. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essentia
Host	Mouse
Immunogen Region	E. coli-derived human DCK recombinant protein (Position: E17-L260).
Isotype	Mouse IgG2b
Molecular Weight	30 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Deoxycytidine kinase; dCK; DCK
Tissue Specificity	Expressed ubiquitously in normal tissues.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P27707
Gene Id	1633
Gene Name	DCK
Clone No	Clone: 3G10
Subcellular Location	Nucleus

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunocytochemistry/Immunofluorescence, 2 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Chottiner, E. G., Shewach, D. S., Datta, N. S., Ashcraft, E., Gribbin, D., Ginsburg, D., Fox, I. H., Mitchell, B. S. Cloning and expression of human deoxycytidine kinase cDNA. Proc. Nat. Acad. Sci. 88: 1531-1535, 1991.<br /><br />2. Stegmann, A. P. A., Honders, M. W., Bolk, M. W. J., Wessels, J., Willemze, R., Landegent, J. E.Assignment of the human deoxycytidine kinase (DCK) gene to chromosome 4 band q13.3-q21.1. Genomics 17: 528-529, 1993.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002381-1	M01655	-	100 ug	$370		Add to Cart
BHA21002381-2	M01655-10ug	Sample	10 ug	$99		Add to Cart
BHA21002381-3	M01655-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002381-4	M01655-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002381-5	M01655-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002381-6	M01655-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002381-7	M01655-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002381-8	M01655-FITC	FITC	100 ug	$570		Add to Cart
BHA21002381-9	M01655-HRP	HRP	100 ug	$570		Add to Cart
BHA21002381-10	M01655-APC	APC	100 ug	$670		Add to Cart
BHA21002381-11	M01655-PE	PE	100 ug	$670		Add to Cart
BHA21002381-12	M01655-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002381-13	M01655-carrier-free	carrier-free	100 ug	$370		Add to Cart

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