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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Cyclophilin E/PPIE Antibody Picoband® (monoclonal, 4I9)

SKU : BHA21003511

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Mfr.No.	M08021, M08021-10ug, M08021-Biotin, M08021-Cy3, M08021-Dylight488, M08021-Dylight550, M08021-Dylight594, M08021-FITC, M08021-HRP, M08021-APC, M08021-PE, M08021-iFluor647, M08021-carrier-free
Alternative Names	chaperonin containing TCP1 subunit 3
Background	Peptidylprolyl isomerase E (cyclophilin E), also known as PPIE, is an enzyme which in humans is encoded by the PPIE gene on chromosome 1. The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alteative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Cyclophilin E/PPIE Antibody Picoband® (monoclonal, 4I9) catalog # M08021. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	E.coli-derived human Cyclophilin E/PPIE recombinant protein (Position: M1-V301).
Isotype	Mouse IgG2b
Molecular Weight	35 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q9UNP9
Gene Id	10450
Gene Name	PPIE
Clone No	Clone: 4I9
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Kim, J.-O., Nau, M. M., Allikian, K. A., Makela, T. P., Alitalo, K., Johnson, B. E., Kelley, M. J. Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines. Oncogene 17: 1019-1026, 1998. 2. Mi, H., Kops, O., Zimmermann, E., Jaschke, A., Tropschug, M. A nuclear RNA-binding cyclophilin in human T cells. FEBS Lett. 398: 201-205, 1996.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003511-1	M08021	-	100 ug	$370		Add to Cart
BHA21003511-2	M08021-10ug	Sample	10 ug	$99		Add to Cart
BHA21003511-3	M08021-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003511-4	M08021-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003511-5	M08021-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003511-6	M08021-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003511-7	M08021-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003511-8	M08021-FITC	FITC	100 ug	$570		Add to Cart
BHA21003511-9	M08021-HRP	HRP	100 ug	$570		Add to Cart
BHA21003511-10	M08021-APC	APC	100 ug	$670		Add to Cart
BHA21003511-11	M08021-PE	PE	100 ug	$670		Add to Cart
BHA21003511-12	M08021-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003511-13	M08021-carrier-free	carrier-free	100 ug	$370		Add to Cart

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