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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD8A

SKU : BHA15100395

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Mfr.No.	AMA05-5M
Clonality	Monoclonal
Description	CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell- cell interaction within the immune system. The dimeric cell-surface glycoprotein CD8 is crucial to the positive selection of cytotoxic T cells in the thymus. It acts as a co receptor with the T-cell receptor on the T lymphocytes to recognize antigens displayed by an antigen presenting cell in the context of class 1 MHC molecules. The co receptor functions as either a homodimer composed of 2 alpha chains or as a heterodimer composed of one alpha and one beta chain. Both chains share significant homology to immunoglobulin variable light chains. A study has confirmed that CD8 expression is a recurrent albeit rare phenomenon in patients with CLL and suggests that CD8 expression has an adverse prognostic impact. Therefore, CD8 expression should be further investigated for its potential to contribute to risk stratification in patients with CLL.
Host	Mouse
Isotype	IgG1 Kappa
Reactivity	Human
Species	Mouse

Clone No	C8/468
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA05-5M	AMA05-5M	6 mL	$319		Add to Cart
AMA05-10M	AMA05-10M	100 tests - i6000	$543		Add to Cart
AXA05-50D	AXA05-50D	50 tests - Xmatrx	$336		Add to Cart
AXA05-YCD	AXA05-YCD	160 tests - Xmatrx	$815		Add to Cart
MUA05-UC	MUA05-UC	1ml Conc	$705		Add to Cart
MUA05-5UC	MUA05-5UC	0.5ml Conc	$492		Add to Cart

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