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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD79b Antibody Picoband®(monoclonal, 6H11)

SKU : BHA21002445

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Mfr.No.	M01399-1, M01399-1-10ug, M01399-1-Biotin, M01399-1-Cy3, M01399-1-Dylight488, M01399-1-Dylight550, M01399-1-Dylight594, M01399-1-FITC, M01399-1-HRP, M01399-1-APC, M01399-1-PE, M01399-1-iFluor647, M01399-1-carrier-free
Alternative Names	B-cell antigen receptor complex-associated protein beta chain
Background	CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene. By fluorescence in situ hybridization, It is mapped to 17q23.3. The CD79B protein together with the related CD79A protein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also can enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CD79b Antibody Picoband® (monoclonal, 6H11) catalog # M01399-1. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL
Host	Mouse
Immunogen Region	E.coli-derived human CD79b recombinant protein (Position: A29-E229). Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.
Isotype	Mouse IgG1
Molecular Weight	35 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD79b; CD79B; B29, IGB
Tissue Specificity	Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P40259
Gene Id	974
Gene Name	CD79B
Clone No	Clone: 6H11
Subcellular Location	Nucleolus. Perinuclear region.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat<br>

Reference	1. "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta"<br /><br />2. Dobbs, A. K., Yang, T., Farmer, D., Kager, L., Parolini, O., Conley, M. E. Cutting edge: a hypomorphic mutation in Ig-beta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development. J. Immun. 179: 2055-2059, 2007.<br /><br />3. Wood, W. J., Jr., Thompson, A. A., Korenberg, J., Chen, X., May, W., Wall, R., Denny, C. T. Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics 16: 187-192, 1993.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002445-1	M01399-1	-	100 ug	$370		Add to Cart
BHA21002445-2	M01399-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21002445-3	M01399-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002445-4	M01399-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002445-5	M01399-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002445-6	M01399-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002445-7	M01399-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002445-8	M01399-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21002445-9	M01399-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21002445-10	M01399-1-APC	APC	100 ug	$670		Add to Cart
BHA21002445-11	M01399-1-PE	PE	100 ug	$670		Add to Cart
BHA21002445-12	M01399-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002445-13	M01399-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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