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Home / Primary Antibodies / Monoclonal Antibodies

Anti-c-Jun

SKU : BHA15100364

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BioGenex Laboratories

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Mfr.No.	AM958-5M
Clonality	Monoclonal
Description	c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. c-Jun antibodies are used to study the signal-transducing transcription factor of the AP1 family. c-Jun has been implicated in several areas of cell biology including cell cycle progression through the G1 phase, transformation and differentiation and has recently been linked to apoptosis. As well as its cell cycle attributes, c-Jun is a known proto-oncogene and is found to be significantly overexpressed in lung and breast cancers, making it a viable tumor marker.
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	4H9
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM958-5M	AM958-5M	6 mL	$421		Add to Cart
AM958-10M	AM958-10M	100 tests - i6000	$795		Add to Cart
AX958-50D	AX958-50D	50 tests - Xmatrx	$441		Add to Cart
AX958-YCD	AX958-YCD	160 tests - Xmatrx	$1126		Add to Cart
MU958-UC	MU958-UC	1ml Conc	$1772		Add to Cart
MU958-5UC	MU958-5UC	0.5ml Conc	$1062		Add to Cart

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