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Home / Primary Antibodies / Monoclonal Antibodies

Anti-BOB-1

SKU : BHA15100363

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BioGenex Laboratories

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Mfr.No.	AN957-5M
Clonality	Monoclonal
Description	The BOB.1 / OBF.1 / OCA-B protein is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. BOB-1 facilitates transactivation of immunoglobulins and other B-cell specific genes through the binding and activation of the transcription factors Oct-1 and Oct-2. Research studies have demonstrated that BOB-1 expression is required for antigen-dependent B-cell maturation. Expression of BOB.1/OBF.1 is restricted largely to mature B-cells. In pathological conditions such as classical Hodgkins disease, loss of BOB-1 expression is thought, in part, to contribute to the defect in immunoglobulin gene expression by Hodgkin and Reed Sternberg cells. Expression of BOB.1/OBF.1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	SP92
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN957-5M	AN957-5M	6 mL	$251		Add to Cart
AN957-10M	AN957-10M	100 tests - i6000	$548		Add to Cart
AY957-50D	AY957-50D	50 tests - Xmatrx	$305		Add to Cart
AY957-YCD	AY957-YCD	160 tests - Xmatrx	$778		Add to Cart
NU957-UC	NU957-UC	1ml Conc	$1249		Add to Cart
NU957-5UC	NU957-5UC	0.5ml Conc	$752		Add to Cart

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