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Home / Primary Antibodies / Monoclonal Antibodies

Anti-BCL2 Antibody

SKU : BHA14800094

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GenomeMe Lab Inc

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Mfr.No.	IHC514-7
Clonality	Monoclonal
Description	B-Cell Lymphoma 2 (BCL2) is involved in regulation of cell apoptosis by controlling mitochondrial permeability and release of cytochrome c. It also has critical roles in normal cell physiology related to neuronal activity, autophagy, calcium handling, mitochondrial dynamics, and energetics. BCL2 overexpression has been shown to promote cell survival by suppressing apoptosis, and is found to be correlated with poor disease prognosis in breast, prostate, ovarian, endometrial, and colon cancers. In follicular lymphoma, Anti-BCL2 reacts negatively with germinal centers and positively with neoplastic follicles. In lymphoid lesions, BCL2 staining is useful for distinguishing reactive and neoplastic follicular proliferations, and for identifying minimal residual disease in the bone marrow of follicular lymphoma patients. BCL2 is now a useful target of human cancer therapy.
Host	Mouse
Isotype	IgG1
Species	Human

Clone No	IHC514

Buffer	Tris Buffer pH7.6 with BSA, and sodium azide as preservative
Storage	-20 degrees Celsius

Applications	WB, IHC, ELISA
Dilution	1:200

Product Manual	MSDS

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SKU	Supplier No.	Size	Your price	Quantity
BHA14800094	IHC514-7	7ml RTU Predilute	$105		Add to Cart

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