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Home / Primary Antibodies / Monoclonal Antibodies

5-Lipoxygenase Antibody / ALOX5

SKU : BHA17109980

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NSJ Bioreagents

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Mfr.No.	RQ5292
Clonality	Monoclonal
Description	The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	Arachidonate 5-Lipoxygenase
Uniprot	P09917
Clone No	AECE-1

Format	Purified
Purification	Affinity purified
Storage	Store the 5-Lipoxygenase antibody at -20°C.

Applications	WB
Dilution	Western blot: 1:500-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109980	RQ5292	100ul	$439		Add to Cart

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