Leptin (obesity homolog, mouse) Adenovirus (Ad-LEPTIN)

Mfr.No.	1441
Description	This gene is similar to the mouse obesity gene (ob). The protein encoded by this gene is secreted by white adipocytes. In the mouse study, mutations in this gene are linked to severe and morbid obesity. The recessive obesity mutation, Ob, identified in 1950, results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. It has been postulated that the Ob gene product may represent a component of a signaling pathway in adipose tissue that functions to regulate body fat depot size. Ob encodes a 4.5 kb adipose tissue-specific mRNA with a highly conserved 167 amino acid open reading frame. The Ob gene product has been identified as a 16 kDa secreted protein, designated leptin, that is apparently produced only in adipose tissue.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	LEPTIN
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600139	1441	200 µL	$475		Add to Cart