Kras is a member of the RAS protein family - a class of small GTPases involved in cell signaling. It plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Product Type
Recombinant Proteins
Tag
Polyhistidine
Field of Use
Drug Targets
Molecular Weight
46 kDa
Species
Human
Application
ELISA, Western Blot, Inhibitor Screening, GDP/GTP Nucleotide Exchange Reaction, Binding Assay, Immunoaffinity Purification, Protein Array.
Expression Source
E. coli
Protein Length
169 aa
Uniprot
P01116
Shipping
Dry Ice
Purity
>95%, SDS-PAGE
Storage
Stable for 12 months at -80°C, Avoid freeze/thaw cycles