MHC Class II (I-A/I-E) -KO

Mfr.No.	NM-KO-18032
Description	All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1,H2-Aa,H2-Eb1,H2-Eb2,H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins. NCBI ID: 14961 MGI ID: 103070 Ensembl ID: ENSMUSG00000073421 Pubmed: H2-Ab1 Human Ortholog: HLA-DQB2
Nomenclature	C57BL/6Smoc-H2-Ab1^em1H2-Aa^em1 H2-Eb1^em1H2-Eb2^em1H2-Ea-ps^{em1 Smoc}
Strain	Repository Live
KI/KO Gene	H2-Ab1
Synonyms	IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta

Research Application	Immunodeficient, Immune System

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