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Home / Primary Antibodies / IHC Antibodies

WNT1 Antibody

SKU : BHA10559790

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA210558
Alternative Names	ONCOGENE INT1; wingless-type MMTV integration site family; member 1; INT1; Proto-oncogene protein Wnt-1 [Precursor]
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.van Ooyen A., EMBO J. 4:2905-2909(1985).The MGC Project Team; Genome Res. 14:2121-2127(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human WNT1.
Involvement In Disease	Osteoporosis (OSTEOP); Osteogenesis imperfecta 15 (OI15); Osteogenesis imperfecta 14 (OI14)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development. van Ooyen A., EMBO J. 4:2905-2909(1985). The MGC Project Team; Genome Res. 14:2121-2127(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total WNT1 protein.
Subcellular Location	Secreted, extracellular space, extracellular matrix

Uniprot	P04628
Database Links	HGNC:12774 OMIM:164820 KEGG:hsa:7471 STRING:9606.ENSP00000293549 UniGene:Hs.248164
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation
Pathway	Hippo signaling pathway Melanogenesis mTOR signaling pathway Wnt signaling pathway Signaling pathways regulating pluripotency of stem cells Excitatory synapse pathway Inhibitors of axonal regeneration
Protein Families	Wnt family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559790	CSB-PA210558	100ul	$297		Add to Cart

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