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Home / Primary Antibodies / IHC Antibodies

TNFSF12 Antibody

SKU : BHA10559798

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA152148
Alternative Names	Tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; Tumor necrosis factor ligand superfamily member 12
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).Marsters S.A., Curr. Biol. 8:525-528(1998).Clark H.F., Genome Res. 13:2265-2270(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TNF12.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997). Marsters S.A., Curr. Biol. 8:525-528(1998). Clark H.F., Genome Res. 13:2265-2270(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TNF12 protein.
Subcellular Location	Cell membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Tumor necrosis factor ligand superfamily member 12, secreted form: Secreted, SUBCELLULAR LOCATION: Isoform TWE-PRIL: Cell membrane, Single-pass membrane protein

Uniprot	O43508
Gene Id	8742
Database Links	HGNC:11927 OMIM:602695 KEGG:hsa:407977 UniGene:Hs.54673
Function	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Protein Families	Tumor necrosis factor family
Tissue Specificity	Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
Weight	36,589 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559798	CSB-PA152148	100ul	$297		Add to Cart

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