Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Host
Rabbit
Immunogen
Peptide sequence around aa. 778~782 (R-L-S-P-P) derived from Human STAT5A.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total STAT5A protein.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.