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Home / Primary Antibodies / IHC Antibodies

SNCA Antibody

SKU : BHA10559211

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA036896
Alternative Names	NACP; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; SYN; SYUA
Categories	Primary Antibodies
Clonality	polyclonal
Description	May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023. Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569. Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552. Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human synuclein.
Involvement In Disease	Parkinson disease 1, autosomal dominant (PARK1); Parkinson disease 4, autosomal dominant (PARK4); Dementia Lewy body (DLB)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023. Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569. Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552. Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Synuclein protein.
Subcellular Location	Cytoplasm, cytosol, Membrane, Nucleus, Cell junction, synapse, Secreted

Uniprot	P37840
Gene Id	6622
Database Links	HGNC:11138 OMIM:127750 KEGG:hsa:6622 STRING:9606.ENSP00000338345 UniGene:Hs.21374
Function	May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Protein Families	Synuclein family
Tissue Specificity	Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
Weight	14460 MW

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559211	CSB-PA036896	100ul	$297		Add to Cart

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