SRY (sex determining region Y)-Box 2 or SOX-2, is a transcription factor that regulates the pluripotency of undifferentiated embryonic stem cells, and regulates gene expression in the stomach. It is a valuable tool to study stage I lung adenocarcinomas as it has been indicated to be a predictor of poor prognosis. It may be used to detect squamous cell carcinomas of the lung and gastrointestinal tract, and embryonal carcinoma.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG
Raised In
Rabbit
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
SOX-2
Note
1:50-1:200
Clone No
IHC129
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.