SensiStainTM Anti-p27 Antibody detects for the presence or absence of p27 or 27 Kip1, a cyclin-dependent kinase inhibitor that binds to and inhibits cyclin-dependent kinases, thereby regulating progression from G1 to S phase. It has been associated with poor prognosis in certain cancers, such as colon carcinoma, small breast carcinomas, non-small-cell lung carcinoma, and hepatocellular carcinoma, when p27 levels are decreased in expression.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG1
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
p27
Note
1:50-1:200
Clone No
IHC128
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.