SensiStainTM Anti-PAX8 Antibody is in ready-to-use format. PAX-8 belongs to the paired box (PAX) family of transcription factors which play an important role in early development such as with thyroid follicular cells and the expression of thyroid-specific genes; however mutations in the PAX8 gene is found to be associated with thyroid follicular carcinomas. PAX-8 is also found to be expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes. PAX8 has been found to be as useful marker for renal epithelial tumors, ovarian cancer and for differential diagnoses in lung and neck tumors. Anti-PAX-8 can be used in conjunction with other markers such as uroplakin, mammaglobin and TTF-1 to determine the primary sites of invasive micropapilary carcinomas of ovary.
Formulation
Liquid
Host
Mouse(Mu)
Guarantee
abm guarantees that all our SensiStain™ Anti-PAX8 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen
Recombinant Human PAX8
Isotype
IgG2a
Quantity
100 µg/ 100 µl
Recommended Dilution
IHC: 1:1000-1:3000; WB: 1:500-1:1000
Relevance
UniProtKB: Q06710
Shipping Condition
Ice Packs
Species Reactivity
Human
Specificity
Human PAX-8
Gene Name
PAX8
Clone No
AHC0210
Concentration
100 µg/ 100 µl
Purity
Protein A/G Affinity Purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.