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Home / Primary Antibodies / IHC Antibodies

PTH1R Antibody

SKU : BHA10557266

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA018988KA01HU
Alternative Names	PTH1R; PFE; PTHR; PTHR1
Categories	Primary Antibodies
Description	The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansens metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Hgnc	9608
Host	Rabbit
Immunogen	Recombinant protein of human PTH1R
Intended Use	For research use only. Not for human, diagnostic or therapeutic use.
Involvement In Disease	Jansen metaphyseal chondrodysplasia (JMC); Chondrodysplasia Blomstrand type (BOCD); Enchondromatosis multiple (ENCHOM); Eiken skeletal dysplasia (EISD); Primary failure of tooth eruption (PFE)
Isotype	IgG
Mgi	97801
Raised In	Rabbit
Reactivity	Human, Rat
Regulatory	RUO
Relevance	The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansens metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Size	100μl(100μg)
Species	Homo Sapiens (Human)
Subcellular Location	Cell membrane, Multi-pass membrane protein

Rgd	3442
Target Details	This protein is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.
Uniprot	Q03431
Database Links	HGNC:9608 OMIM:125350 KEGG:hsa:5745 STRING:9606.ENSP00000321999 UniGene:Hs.1019
Function	Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Protein Families	G-protein coupled receptor 2 family
Tissue Specificity	Expressed in most tissues. Most abundant in kidney, bone and liver.

Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Format	liquid
Purification	Affinity purification
Purity	Affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Tested Application

ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557266	CSB-PA018988KA01HU	100μl	$387.33		Add to Cart

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