May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.Koichi Kusuhara, J. Virol., Oct 1999; 73: 8112 - 8119. Isis Rivera-Walsh, J. Biol. Chem., Aug 2000; 275: 25222.Eric D. Tang, J. Biol. Chem., Sep 2003; 278: 37297 - 37305.Isis Rivera-Walsh, J. Biol. Chem., Oct 2001; 276: 40385 - 40388.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human JM4.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.
Koichi Kusuhara, J. Virol., Oct 1999; 73: 8112 - 8119. Isis Rivera-Walsh, J. Biol. Chem., Aug 2000; 275: 25222. Eric D. Tang, J. Biol. Chem., Sep 2003; 278: 37297 - 37305. Isis Rivera-Walsh, J. Biol. Chem., Oct 2001; 276: 40385 - 40388.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total JM4 protein.
May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis.
Protein Families
PRA1 family
Tissue Specificity
Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.