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Home / Primary Antibodies / IHC Antibodies

POLG2 Antibody

SKU : BHA10558381

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA826673
Alternative Names	DNA polymerase subunit gamma-2; mitochondrial; EC 2.7.7.7; Mitochondrial DNA polymerase accessory subunit; PolG-beta
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA.Lim S.E., J. Biol. Chem. 274:38197-38203(1999).Johnson A.A., Biochemistry 39:1702-1708(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human POLG2.
Involvement In Disease	Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 4 (PEOA4)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA. Lim S.E., J. Biol. Chem. 274:38197-38203(1999). Johnson A.A., Biochemistry 39:1702-1708(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total POLG2 protein.
Subcellular Location	Mitochondrion

Uniprot	Q9UHN1
Database Links	HGNC:9180 OMIM:604983 KEGG:hsa:11232 STRING:9606.ENSP00000442563 UniGene:Hs.437009
Function	Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558381	CSB-PA826673	100ul	$297		Add to Cart

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