PIH1D1 Antibody

Mfr.No.	CSB-PA889130LA01HU
Alternative Names	PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog), PIH1D1, NOP17
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Host	Rabbit
Immunogen	Recombinant Human PIH1 domain-containing protein 1 protein (1-290AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Species	Homo Sapiens (Human)

Uniprot	Q9NWS0
Database Links	HGNC:26075 OMIM:611480 KEGG:hsa:55011 STRING:9606.ENSP00000262265 UniGene:Hs.5245
Function	Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles
Protein Families	PIH1 family, PIH1 family
Research Area	Others
Tissue Specificity	Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skele

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Format	Liquid
Purification	>95%, Protein G purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Applications

ELISA, IHC, IF, IP

Description

ELISA ; IHC ; IF ; IP, IP ; ELISA ; IHC ; IF

Dilution

Tested Application

ELISA, IHC, IF, IP; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500, IP:1:200-1:2000

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10517663	CSB-PA889130LA01HU	100ug	$299		Add to Cart
BHA10517663	CSB-PA889130LA01HU	50ug	$166		Add to Cart