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Home / Primary Antibodies / IHC Antibodies

Phospho-STAT5B (Ser731) Antibody

SKU : BHA10560508

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA220945
Alternative Names	Signal transducer and activator of transcription 5B
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of serine 731 (A-P-S(p)-P-A) derived from Human STAT5B.
Involvement In Disease	Growth hormone insensitivity with immunodeficiency (GHII)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of STAT5B only when phosphorylated at serine 731.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P51692
Database Links	HGNC:11367 OMIM:245590 KEGG:hsa:6777 STRING:9606.ENSP00000293328 UniGene:Hs.595276
Function	Carries out a dual function
Pathway	Chemokine signaling pathway ErbB signaling pathway Jak-STAT signaling pathway Necroptosis Th1 and Th2 cell differentiation Th17 cell differentiation AGE-RAGE signaling pathway in diabetic complications
Protein Families	Transcription factor STAT family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560508	CSB-PA220945	100ul	$360		Add to Cart

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